Alzheimer’s Disease Signs and Symptoms Help Identify Alzheimer’s Disease Early

There are a number Alzheimer’s disease signs and symptoms to be on the lookout for which can help diagnose this disease. The most prominent which is memory loss? What seems to be a simple mistake in memory may be the start of Alzheimer’s. Anyone can suffer short periods of forgetfulness. Alzheimer’s is much more than that; it actually attacks your short-term memory first. Then slowly keeps progressing.

Since 1906 when the German born psychiatrist Alois Alzheimer first discovered Alzheimer’s disease in a patient, until this very day. Alzheimer’s remains a fatal ailment that has both absolutely no cause as well as no known cure.

There are however medications to help slow this disease from developing into its final stages. In addition there are drugs already available that can assist the sufferer and manage the side effects of depression, hallucinations and delusions.

As Alzheimer’s disease signs and symptoms progress the patient will start to forget familiar things and will begin to lose well-known skills. The patient will begin to start forgetting people’s names. Then they will actually become unable to identify their friends and family.

It wouldn’t be fair to blame all memory loss on Alzheimer’s disease. There are two basic reasons for memory loss. Naturally the patient’s age is a factor.One of Ten people 65 years of age and older will be experiencing some form of Alzheimer’s. And 50% of people 85 years of age and older will also experience some form, Alzheimer’s.

Presently here in United States as of 2011 there are over 5 million sufferers. As the baby boomer generation begins to reach their golden years, this monster of a disease will be waiting for them. The first early sign of Alzheimer’s is memory loss. Alzheimer’s disease will first attack the frontal lobe where the short-term memory is stored, and in many cases not affect the patient’s long-term memory. But as the disease progresses the patient will lose more and more of their skills. It will affect the way an individual thinks their ability to speak, and their behavior.

The patient will become indecisive and can start having trouble within decision-making processes. These lapses of memory as well as cognitive functions are based on the frontal as well as temporal lobes of the brain.

The patient may experience mood swings and may become violent or even excessive passivity. The later on stages will be more terrible. Alzheimer’s patients will begin to loss control of their body functions and muscle control as well as mobility.

Alzheimer’s generally develops and become deadly within approximately 5 to 20 years.

Since Dr. Alzheimer identified the disease in 1903, there have been medical breakthroughs and research studies that have been discovered to be beneficial in preventing or even delaying Alzheimer’s disease.

Researchers believe that physical exercise and eating properly can reduce the chance of contracting this disease.people with high blood pressure and high levels of cholesterol, and low levels of vitamin b appeared to be at higher risk of getting Alzheimer’s disease.

Alzheimer’s Disease From Oxidative Stress

  • Alzheimer’s Disease is the 6th leading cause of death in the United States.
  • One in three seniors die with Alzheimer’s and it kills more than breast cancer and prostate cancer combined
  • In 2019 Alzheimer’s is costing the nation $290 billion. By 2050 that is expected to rise to $1.1 trillion
  • Among people age 70, 61% of those with Alzheimer’s dementia are expected to die before the age of 80 compared with 30% of people without Alzheimer’s – a rate twice as high
  • The saddest stat of all: Only 16% of seniors receive cognitive assessments in doctors’ checkups.

Harvard: Inflammation is the unifying link between all diseases – Mental & physical. Oxidative stress, if uncontrolled leads to inflammation.

Quick review of oxidative stress (I have many articles here to check out on oxidative stress). An imbalance in our redox state as a result of increased free radicals and a decrease in antioxidant defense. Free radicals are molecules that contains one or more unpaired electrons in its outer shell, trying to rebalance itself by snatching another molecule’s electrons. This imbalance causes a significant decrease in the effectiveness of antioxidant defenses, such as glutathione.

There are many causes of oxidative stress, both endogenous & exogenous, and unfortunately in unavoidable. Again, please refer to my many other articles here.

Pubmed: Tissues and organs, particularly the brain, a vulnerable organ, are affected by ROS due to its composition. The brain is largely composed of easily oxidizable lipids while featuring a high oxygen consumption rate. In other words – the brain is an easy target to suffer the ravages of inflammation.

Now: If we all learned about oxidative stress, how to minimize it – maybe we could prevent a lot of these cases of Alzheimer’s – and the other top diseases killing us?

More and more research is proving Alzheimer’s disease pathology is of oxidative stress. This Alzheimer’s Disease related increase in oxidative stress has been attributed to decreased levels of the brain antioxidant, glutathione.

A 2018 human study published in the Journal of Alzheimer’s Disease, showed glutathione to be significantly depleted in Alzheimer’s patients compared to those without Alzheimer’s. Glutathione is accepted as the omnipotent anti-oxidant that protects the brain from free radical damage. Researchers are hoping these findings will give us another measure to use when diagnosing potential for the advancement of Alzheimer’s disease or recognizing those that are in the early stages of advancement.

Ways to increase glutathione:

  • Spinach, avocados, asparagus
  • sulphur rich foods: Beef, fish, poultry. To a lesser extent vegetables such as cruciferous vegetables and allium vegetables (garlic and onion, don’t brown it!)
  • vitamin C rich foods
  • Selenium rich foods (please no Selenium supplements – it can be toxic)

Heart disease, stroke, cancers, diabetes… all of our top killers are, oxidative stress is a major factor in all of them. Learning how to properly control oxidative stress, really what a proactive lifestyle is all about.

Poetry As a Means to Negotiate Alzheimer’s and Other Dementia Related Diseases

Book Review:

Kakugawa, Frances H. Breaking the Silence: A Caregiver’s Voice. Nevada City, California: Willow Valley Press, 2010.

Despite striking achievements of science and technology, the problems of human life and destiny have not ended, nor have the solutions been seriously affected by scientific knowledge. Alzheimer’s disease, which currently affects about 10% of people over 65 years of age and 50% of those over 85 years of age, has no cure. As many as 5.3 million Americans are now living with the devastating disease. According to a study, unless new treatments are developed to decrease the likelihood of Alzheimer’s disease, the number of individuals with Alzheimer’s disease in the USA may rise to 14 million by the end of the year 2050.

Read against this background, Frances Kakugawa’s book, a mix of poetry, story and practical guide, is a recognition of the services rendered by professional and voluntary organizations that seek to minimize the pangs of Alzheimer’s sufferers as well as the sufferings of their near and dear ones. It pays tribute to caregivers who have been untiringly working for creation of a world without dementia, stroke, or cancer just as it seeks to help them endure the innumerable crises of caregiving.

Breaking the Silence: A Caregiver’s Voice merges Frances Kakugawa and her poet-colleagues’ varied experiences with a broad human perspective, engaging both mind and heart. The caregivers seek to share their compassionate spirit with a sense of gratitude to all those who help the victims of Alzheimer’s disease negotiate their mentally vacant existence. They are not only aware of the sufferers’ substantial loss of brain cells or progressive decline in their ability to think, remember, reason, and imagine, or their language problems and unpredictable behavior, confusion, or loss of sensory processing, but they also know well how the Alzheimer’s victims suffer a sort of living death, becoming a mere body stripped of its humanity. They have been witness to caregiving family members of increasingly confused and helpless sufferers themselves often becoming the disease’s exasperated and exhausted victims:

” Is she the mom who nurtured me?

Is it the dementia playing havoc with my mind?

Or is this really my mom? I don’t know.”

(‘More Glimpses of a Daughter and Mother’)

and

“I am torn between two needy factions.

Mom unaware, daughter pushing all boundaries

Both out of control.”

(‘The Sandwich’)

For Frances Kakugawa, caregiving is a mission even as the memory and image of her Alzheimer’s struck mother persists in her life as a “loud presence”. She gives voice to many caregivers who are ever worried about their loved ones not even able to carry out the simplest tasks and/or are completely dependent on others for their care. She expresses the very haunting fear of death:

“Is she breathing? Is she alive?

Is she finally gone, freeing me once again?

I continue my sentinel watch.”

(‘Unspoken Mornings’)

Frances not only articulates their fear but also learns to negotiate it by boldly facing it as part of life. In fact, she turns the metaphor of death as integral to life, be it in the form of “an ache of emptiness”, “unfulfilled dreams”, or “unlived moments”. In her deeper silences, she explores the very meaning of life:

“A second gust of wind

Lifts another fistful of ashes.

Be still and listen.”

(‘Song of the Wind’)

It is hearing the inner silence, which is something meditative, Biblical, and spiritual. It is awaking to the self, the Holy Spirit, the Divine himself. When the soul peaks into silence, human becomes divine. She sounds earnest and exceptional, seeking harmony with the highest ideals, irrespective of chaotic personal experiences. As Setsuko Yoshida says in ‘Can I?’:

“Poems by Frances this morning

Reveal the feelings of ‘divine’

In caregiving.”

In fact, as women poets, Frances Kakugawa and her caregiver colleagues (Elaine Okazaki, Linda McCall Nagata, Eugene Mitchell, and others) present a feminine and yet very humane perspective to the dementia-related illnesses. Jason Y. Kimura, Rod Masumoto, and Red Silver, though male poets, demonstrate the ‘Prakriti’ or ‘Yin’ aspects in rhythm with other contributing caregivers’ sensibility. They variously turn the Alzheimer’s into a metaphor for the loss of language, the loss of memory, and the loss of voice. Their poetry, often brief and personal, and rich and insightful, becomes a means to communicate the sufferers’ loss of feeling, love, dignity, honor, name, and relationship; in short, their isolation, or threat to living itself:

“All my life I have lived

With crayons in one hand,

Filling in spaces,

Spaces left by departed lovers, family, friends,

Leaving me crayons smashed against walls

Creating more grief than art.”

(‘Empty Spaces’)

They also use the metaphor for challenge to survive, to exist, without fears and anxieties:

“I am woman,

Suppressed,

Dying.”

(‘Nissei Woman’)

and

“I am not merely heaven, man and earth

Rooted by cultural hands.

Sift those sands. Yes!

I am free!

I am tossed into the winds.

I shed my kimonos.

I spread my legs.

I am free.”

(‘Lesson #3’)

and

“When I am 88

I will still be woman,

Yes!”

(”When I am 88′)

and

“I am still here

Help me remain a human being

In this shell of a woman I have become.

In my world of silence, I am still here.

Oh, I am still here.”

(‘Emily Dickinson, I am Somebody’)

They convert the Alzheimer’s into a search for reprogramming the mind, the thought, and the attitude to overcome the irreversible suffering and helplessness. As Frances very feelingly asserts: it is the search for

“…the same umbilical cord

That once set me free

Now pulls and tugs me back

To where I had begun.

There must be hidden

Somewhere a gift very divine

In this journey back.”

(‘Mother Into Child, Child Into Mother’)

They are true to themselves as they voice their search for the whole. With an empathetic awareness, they disclose their innate goodness, trust, and compassion to make a “symphony of truth.” At the core of their musing lies a desire to integrate themselves, to live in time as well as in eternity:

“What other path is there

Except the divine

Where love, kindness, compassion,

Help me discover little pieces of myself

That make me smile

Bring me such quiet joy

At the end of each day.”

(‘Bless the Divine’)

They reveal the working of the primal impulses of the human soul which rises above the differences of race and of geographical position. In short, they give vent to the thought of all people in all lands.

As poet-caregivers they cope with their tensions, fears and anxieties through introspection, and accommodate their inner and outer conflicts, sufferings and celebrations through imaginative insight. They mirror the broad social or familial conditions as well as their own personal state with perceptions that are often different from those of the male poets (or male caregivers). Their quest is for real reality vis-à-vis degeneration, privation, insecurity, helplessness, anonymity, and death. They search for life and live with awareness of what lies beneath the skin of things around, the psycho-spiritual strains, the moral dilemmas, the betrayals, and the paradoxes:

“Why do you say I am sacrificing

Good years of my life

For caring for my mother,

When it shouldn’t be a secret

That I am really living

In a way I have never lived before?



No, this is not sacrifice.

It is just reality.

I am really living

In a way I have never lived before.

I am living love.”

(‘What I Know’)

Against the complexities of experiences, they demonstrate a sense of values such as love, faith, truth, tolerance, patience, peace, charity, harmony, humility, and healthy relationships. They tend to think intuitively and/or turn personal, inward, spiritward, or Godward, without indulging in intellectual abstraction. They write with poetic sensibility. Their metaphors and images reflect their inner landscape as much as their responses to what they observe or experience externally. They are often reticent and honest in their verbal expression, and their inner vibrations touch or elevate the readers’ senses. As they create discourse of themselves as caregivers, they also sound committed to their home, family, children, motherhood, and neighborhood, often voicing their own vision and understanding which cuts across cultures and regions.

They seek to transcend their body or femininity and respect the woman in themselves, even if affected by the Alzheimer’s environment. They turn inside out and reveal what is personal yet universal in their different roles as mother, wife, daughter, and feel the agony of the spirit while trying to know “Who I am?”, or “How I should live, who I should be”, or “What am I looking for? Why did I come?”

As they look back or reflect their present, they also voice the need for strong sense of togetherness vis-à-vis their inner conflicts, spiritual hunger, loneliness, or dependence. They sound challenging the Alzheimer’s itself:

“You could not rob us, though we forgot.

You could not erase us, though we could not write.

You could not silence, though we could not speak.

The stories, the laughter, the moments that passed

Into their keep, you could not steal

Into a night of silence.”

(‘Hey Alzheimer’s’)

As they fill one with hope for ageing with grace and dignity despite the challenges of loss, they create an alternative motive and impulse for social action at a very personal level:

“Through this deepest darkened night

I will hold the light

To take away all your fears.

Just know I will always be near.”

(‘To My Mother’)

There is an urge for changing the situation for themselves, or for being in peace with oneself. The poets and caregivers of Breaking the Silence seek to create a new culture as they rationalize how we ought to live in future.